Recommend both individuals and caregivers about hazards of respiratory depression and sedation when diazepam is used with opioids; advise sufferers never to generate or operate weighty equipment until eventually the results of concomitant use With all the opioid are already established
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topiramate will reduce the extent or impact of diazepam by influencing hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Restrict dosage and duration if concomitantly used; watch closely for respiratory despair and sedation
Coadministration of other CNS depressants or Alcoholic beverages usage may well potentiate CNS-depressant effects of diazepam
Benzodiazepines may perhaps boost pitfalls of abuse, misuse, and addiction, which can lead to overdose or Demise
If atropine, scopolamine or other premedications sought after, they need to be administered in different syringes
lapatinib will enhance the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Monitor.
Controlling your partial-onset seizures may perhaps suggest using a number of antiepileptic medicines. BRIVIACT is actually a prescription drugs that may be utilised to deal with partial-onset seizures in folks 1 thirty day period of age and more mature.
bosentan will decrease the level or influence of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Keep an eye on.
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conivaptan will improve the stage or result of diazepam by affecting hepatic/intestinal enzyme CYP3A4 metabolism. Use Warning/Check.
Abuse and misuse of benzodiazepines usually include concomitant utilization of other remedies, Alcoholic beverages, and/or illicit substances, which happens to be connected to an elevated frequency of serious adverse results; ahead of prescribing and all over treatment method, assess Each and every individual’s hazard for abuse, misuse, and addiction
If symptom aid not obtained immediately after 3rd read more administration, adjunctive therapy appropriate for the condition is suggested Discontinuation or dosage reduction